Derby boss Nigel Clough admits the King Power Stadium has not been a happy hunting ground for the Rams in recent years.
Derby have never won in Leicester since City moved away from Filbert Street, their last victory coming in February 2002.
Clough says his current crop should have picked up more points than the eight points from nine away games they have accrued so far, but says they arrive at City still in good spirits.
"At home, Leicester are in as good form as we are at home, so it will be a tough game. They will be extremely confident," said Clough.
"It has been a difficult place for us to get anything despite playing not that badly at times, but we are in pretty good shape.
"We have had a tough run of games and we have lost only three of 12.
"Five wins and four draws is a pretty good run."
Clough believes his side must show more belief on the road to mirror their impressive home form, where they have been beaten just once.
"We have to take our home form into the away games," said Clough.
"We've been a little reluctant at times to shoot and create chances away from home. We have to get it into our heads to play like we do at Pride Park, which we have done at times."
Clough says the Rams, who play 4-4-2 at home, have struggled to find a system that has suited them on the road, but he added he was confident they could find a system to trouble City this afternoon.
"We have tried 4-4-2, 4-3-3, 4-4-1-1 or whatever, so we will see what best suits us and what can cause Leicester most problems as well," said Clough.
"It is too simplistic to go 4-4-2 every away game, we cannot afford to do that.
"We try to start with a 4-4-2 but we might change during the game, like we did against Cardiff the other night, if we think it is of benefit.
"We have not kept enough clean sheets in away games. We are taking the game to teams home and away.
"We are having the majority of possession in quite a few away games.
"It is about getting the balance between being resilient and also looking to attack."