Leading scorer David Nugent is a doubt for Leicester ahead of Blackburn's visit to the King Power Stadium.
Nugent hurt his neck in a challenge with Blackpool defender Craig Cathcart during Saturday's goalless draw at Bloomfield Road and the 14-goal striker will undergo a late fitness test.
On-loan Tottenham striker Harry Kane impressed on his debut against the Tangerines and he could make his home bow for the Foxes on Tuesday.
Matty James missed out at the weekend with a knock and the midfielder looks like being absent once more.
Ahead of the game, Leicester boss Nigel Pearson told reporters: "Knowing (Blackburn manager) Michael Appleton as I do, he'll try and make his teams difficult to beat.
"I think that's what we all try to do in all honesty, but they've got some good experience within their ranks.
"We know it will be a tough game as they've had some good results of late, but as always my main interest is how we play ourselves.
"I know that if we play to our strengths we've got a very good chance of winning the game."
Blackburn manager Michael Appleton must contend with a growing injury list ahead of the clash.
Colin Kazim-Richards will miss the match after suffering an ankle injury during Saturday's goalless draw against Leeds and the forward is awaiting the results of a scan amid fears he could be sidelined for two to three months.
Midfielder Lee Williamson (ankle) and defender Martin Olsson (eye) also recently started lengthy spells on the sidelines, while Dickson Etuhu is expected to miss the rest of the season due to medial knee ligament damage.
Another serious knee-injury victim, Leon Best, continued his rehabilitation with a goal for Rovers' reserves on Monday afternoon and, although Tuesday's trip to the King Power Stadium comes too soon for the Republic of Ireland international, he may be considered when Peterborough visit Ewood Park on Saturday.
Fabio Nunes (hamstring) is in the same boat as Best, while fellow winger Josh King (hamstring), midfielder David Dunn (calf) and goalkeeper Paul Robinson (back) all remain sidelined.
